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Journal of Child Neurology

 

 

 

 

 

 

J Child Neurol.2006 Jul,21(7):591-5

Long Survival Following Bacterial Meningitis-Associated Brain Destruction

Susan Repertinger, MD

Department of Pathology, Creighton University School of Medicine

William P. Fitzgibbons, MD

Department of Family Medicine, Creighton University School of Medicine

Mathew F. Omojola, MB, FRCPC

Department of Radiology Creighton University School of Medicine, Omaha, NE

Roger A. Brumback, MD

Department of Pathology, Creighton University School of Medicine

This report describes the brain autopsy of a boy who at age 41/2 years experienced an episode of fulminant Haemophilus influenzae type b bacterial meningitis, resulting in massive brain destruction and the clinical signs of brain death. However, medical intervention maintained him for an additional two decades. Subsequent autopsy revealed a calcified intracranial spherical structure weighing 750 g and consisting of a calcified shell containing grumous material and cystic spaces with no recognizable neural elements grossly or microscopically. This case represents an example of long survival of brain death with a living body. (J Child Neurol 2006;21:591595; DOI 10.2310/7010.2006.00137).

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